Peer Reviewed Research
This section includes peer reviewed research articles relevant to multipurpose prevention technologies (MPTs) for reproductive health. Information is listed according to topic area, listed in the right hand navigation.
All Articles
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
Abdool Karim Q, et al. Science. 2010 Sep 3;329(5996):1168-74.
Lactococcus Lactis-Based Vaccines: Current Status and Future Perspectives
Bahey-El-Din M, Gahan Cormac, Human Vaccines. January 2011 7(1) 1-4.
Efficacy Results of a Trial of a Herpes Simplex Vaccine
Belshe RB, et al. New England Journal of Medicine. 2012; 366:34-43.
Sociocultural Issues in the Introduction of Human Papillomavirus Vaccine in Low-Resource Settings
Bingham A, DrakeJK, LaMontagne DS. Archives of Pediatric & Adolescent Medicine. May 2009, Vol 163,5:455-461.
An Approach to Formative Research in HPV Vaccine Introduction Planning in Low-Resource Settings
Bingham A, Janmohamed A, Bartolini R, Creed-Kanashiro HM, Katahoire AR, Khan I,et al. The Open Vaccine Journal. 2009, Vol 2.
Innovative public-private partnerships to maximize the delivery of anti-malarial medicines: lessons learned from the ASAQ Winthrop experience
Bompart F, Kiechel JR, Sebbag R, Pecoul B. Malaria Journal, 2011. Vol 10:143.
Intrauterine device use, cervical infection with human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studies
Castellsague X, Diaz M, Vaccarella S, de Sanjose S, Munoz N, Herrero R, et al. The Lancet.
Hormonal contraception and HIV risk: evaluating marginal-structural-model assumptions
Chen L, Cole SR, Morrison CS, Epidemiology. November 2011 22(6) 877-8.
Family Planning as a Cost-Saving Preventive Health Service
Cleland K, Peipert J, Westhoff C, Spear S, Trussell J, New England Journal of Medicine.
Safety and Immunogenicity of Three Different Formulations of a Liquid Hexavalent Diphtheria–Tetanus–Acellular Pertussis–Inactivated Poliovirus–Haemophilus Influenzae B Conjugate–Hepatitis B Vaccine at 2, 4, 6 and 12–14 Months of Age
Diaz-Mitoma F, Halperin S, Tapiero B, Hoffenbach A, Zappacosta P, Radley D, et al., Vaccine. 29(2011) 1324-1331.
Induction of Immune Memory by a Multisubunit Chlamydial Vaccine
Eko FO, Ekong E, He Q, Black CM, Igietseme JU, Vaccine. 29 (2011) 1472-80.
Reflections on Innovative Medicines Initiative
Goldman M. Nature Reviews Drug Discovery. May 2011, Vol 10:321-322.
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
Heffron R, et al. The Lancet Infectious Diseases. Published online 4 October 2011. DOI:10.1016/S1473-3099(11)70247-X.
Impact of Integrated Family Planning and HIV Care Services on Contraceptive Use and Pregnancy Outcomes: A Retrospective Cohort Study
Kosgei J, Lubano KM, Shen C, Wools-Kaloustian KK, Musick BS, Silka AM, et al., Journal of Acquired Immune Deficiency Syndromes. 15 December 2011 58 (5) 121-26.
The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership
Lacaze C, et al.Malaria Journal. 2011, Vol 10:142.
Failed herpes vaccine puzzles virologists
Ledford H. Nature. Epub 4 January 2012.
Transfer of IgG in the Female Genital Tract by MHC Class I-related Neonatal Fc Receptor (FcRn) Confers Protective Immunity to Vaginal Infection
Li Z, Palaniyandi S, Zeng R, Tuo W, Roopenian D, Zhu X, PNAS 15 March 2011 108(11) 4288-4394.
FcRn Supporting Information
Li et al 10.1073/pnas.10128608
Immunogens and Antigen Processing: Report from a Global HIV Vaccine Enterprise Working Group
Mascola J, King CR, Steinman R, Nature Precedings.
Hormonal contraceptive use and HIV disease progression among women in Uganda and Zimbabwe
Morrison CS, Chen PL, Nankya I, Rinaldi S, et al., Journal of Acquired Immune Deficiency Syndromes. 1 June 2011 57(2) 157-64.
The pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques
Nuttall J, Kashuba A, Wang R, White N, et al., Antimicrobial Agents and Chemothererapy, October 2011.
Virtual drug discovery and development for neglected diseases through public-private partnerships
Nwaka S, Ridley RG. Nature Reviews Drug Discovery. November 2003, Vol 2:920-928.
Mucosal Immuniaztion: A Realistic Alternative
Otczyk D, Cripps A, Human Vaccine. December 2010 6(12) 978-1006.
Effect of Pap Smear Collection and Carageenan on Cervicovaginal Human Papillomavirus-16 Infection in a Rhesus Macaque Model
Roberts J, Kines R, Katki H, Lowy D, Scholler J, Journal of the National Cancer Institute. 6 April 2011 103(7) 1-7.
Genital Transmission of HPV in a Mouse Moel is Potentiated by Nonoxynol-9 and Inhibited by Carrageenan
Roberts J, Buck C, Thompson C, Kines R, Bernardo M, Choyke P, et al., Nature Medicine. July 2007 13(7) 857-61.
Scientists and the media must give a balanced view: A reported link between hormonal contraception and HIV infection deserved a more critical look
Shelton J. Nature. November 2011. Vol 479:7.
Efficacy of Behavioral Interventions to Increase Condom Use and Reduce Sexually Transmitted Infections: A Meta-Analysis, 1991 to 2010
Scott-Sheldon, LAJ, Huedo-Medina TB, Warren MR, Johnson BT, Carey MP. Journal of Acquired Immune Deficiency Syndromes, 15 December 2011 58(5) 489-498.
Baseline correlates of inconsistent and incorrect condom use among sexually active women in the contraceptive CHOICE Project
Shih SL, Kebodeaux CA, Secura GM, Allsworth JE, Madden T, Peipert JF, Sexually Transmitted Diseases. Nov 2011 38(11):1012-19.
HIV/STIs and Pregnancy Prevention, Using a Cervical Barrier and Microbicide
Shihata A, Brody S
World Journal of AIDS, 2011, Vol. 1 131-135
Published Online December 2011 (http://www.SciRP.org/journal/wja)
Assessment of Relevant Cultural Considerations is Essential for the Success of a Vaccine
Stanton B. Journal of Health, Population and Nutrition. September 2004, Vol 22,3:286-292.
Randomized, Placebo-Controlled Phase 2 Trial of a Lactobacillus crispatus Probiotic Given Intravaginally for Prevention of Recurrent Urinary Tract Infection
Stapleton A, Au-Yeung M, Hooton T, Fredricks D, Roberts P, Czaja C, et al., Clinical Infectious Diseases. 2011 52 (10) 1212-17.
Multipurpose Prevention Technologies: Biomedical Tools to Prevent HIV-1, HSV-2, and Unintended Pregnancies
Thurman AR, Clark MR, Doncel GF. Infect Dis Obstet Gynecol. August 2011.
Emerging Antibody Prodictus and Nocotiana Manufacturing
Whaley K, Hiatt A, Zeitlin L, Human Vaccines. March 2011 7(3) 1-8.
Novel Approaches to Vaginal Delivery and Safety of Microbicides: Biopharmaceuticals, Nanoparticles, and Vaccines
Whaley K, Hanes J, Shattock R, Cone R, Friend D, Antiviral Research. December 2010.
Development of Novel Combination Therapies
Woodcock J, Griffin J, Behrman R, New England Journal of Medicine. 17 March 2011 364(11).
Efficient Mucosal Vaccination Mediated by the Neonatal Fc Receptor
Ye L, Zeng R, Bai Y, Roopenian D, Zhu X, Nature Biotechnology. February 2011 29(2) 158-163.
Ye FcRn Supplemental Information
Nature Biotechnology doi: 10.1038.nbt.1742
Behavioral Research on Biomedical Sexual Health Technologies: Opportunities and Directions
Zimet GD. Perspectives on Sexual and Reproductive Health, March 2010, Vol 42,1.
No Author:
Groundbreaking trial results confirm HIV treatment prevents transmission of HIV
UNAIDS/WHO, 12 May 2011. American Journal of Reproductive Immunology, March 2011 65(3).
Special Issue: Sexual Transmission of HIV in the 21st Century